The AI-based program AlphaFold predicts a protein's 3D structure with remarkable accuracy. However, it tends to reduce heterogeneous structures to a single dominant conformation, or shape, and overlooks experimental conditions that can alter local structure. Researchers at the Institute of Scie...
Source: [Phys.org](https://phys.org/news/2026-06-alphafold-ai-tool-conformation-limitation.html)