Scientists at the Department of Energy (DOE)'s Oak Ridge National Laboratory (ORNL) have shown that more than 93% of possible E. coli CRISPR-Cas9 guide RNAs—molecules that direct the gene-editing CRISPR tool to the right spot in DNA—work as intended, a far higher percentage than researchers expe...

Source: [Phys.org](https://phys.org/news/2026-08-sharpening-essential-tool-biotechnology.html)

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