First ever reported cryo-EM visualization of E. coli TGT structure

Phys.org•Wed, Jul 22, 2026, 07:20 PM•2 min read

The enzyme tRNA-guanine transglycosylase (TGT) chemically modifies transfer RNA (tRNA) and plays a key role in how disease-causing bacteria control the production of proteins needed to cause infection. E. coli TGT is nearly identical to the one found in Shigella, which causes the intestinal inf...

Source: [Phys.org](https://phys.org/news/2026-07-cryo-em-visualization-coli-tgt.html)

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